反应详情

温度

120 °C

10 g of 2-amino-3-cyano-4-chloroquinolin and 19 ml of furfurylamine are heated under stirring at 120° C., for 3 hours. The reaction mixture is cooled to 25° C., and six times successively mixed with 50 ml of water, the resulting precipitate is filtered off and dried. The material thus obtained is recrystallized from 60 ml dimethylformamide to obtain 5.8 g of the title compound. Mp.: 206° C.

1. temperatureThe reaction mixture is cooled to 25° C.
2. filtrationthe resulting precipitate is filtered off
3. customdried
4. customThe material thus obtained
5. customis recrystallized from 60 ml dimethylformamide