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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 347819Generated: November 1, 2026

1,3-Cyclohexadiene → Ethyl 2-(1-phenylethyl)-2-azabicyclo[2.2.2]oct-5-ene-3-carboxylate

https://huagongshe.com/reaction/347819

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-CyclohexadieneHCID 11605—
Reactantethyl (1R,3R,4S)-2-[(S)-1-phenylethyl]-2-azabicyclo[2.2.1]hept-5-ene-3-carboxylateHCID 10730826—
ProductEthyl 2-(1-phenylethyl)-2-azabicyclo[2.2.2]oct-5-ene-3-carboxylateHCID 20825292—

Reaction Steps

In the reaction (a) of Example 1, 1,3-cyclohexadiene is used in place of cyclopentadiene to give ethyl 2-(1-phenylethyl)-2-azabicyclo[2.2.2]oct-5-ene-3-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07176217B2
Source datasetuspto-grants-2007_02
ORD IDord-18c96209b77c4114b467024a1e6426e0
Source noteuspto-grants-2007_02