HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Methoxybiphenyl-4-sulfonyl chloride → Ethyl 2-{[4'-methoxy(1,1'-biphenyl)-4-yl]sulfonyl}-2-azabicyclo[2.2.2]octane-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Methoxybiphenyl-4-sulfonyl chloride | HCID 2794750 | — |
| Reactant | Ethyl 2-azabicyclo[2.2.2]octane-3-carboxylate | HCID 19417395 | — |
| Product | Ethyl 2-{[4'-methoxy(1,1'-biphenyl)-4-yl]sulfonyl}-2-azabicyclo[2.2.2]octane-3-carboxylate | HCID 21084205 | — |
Reaction Steps
Ethyl 2-azabicyclo[2.2.2]octane-3-carboxylate is subjected to a reaction similar to the reaction (c) of Example 1 using [4-(4-methoxyphenyl)phenyl]sulfonyl chloride in place of 4-methoxybenzenesulfonyl chloride, to give ethyl 2-{[4′-methoxy(1,1′-biphenyl)-4-yl]sulfonyl}-2-azabicyclo[2.2.2]octane-3-carboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07176217B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-d3ac2d90b01f4312aba93af8f81d8330 |
| Source note | uspto-grants-2007_02 |