Hydrochloric Acid → HCID 49771574, compound

HRID 348695Notes

Reaction equation

HRID 348695 reaction equation
[CH2:1]([N:4]([CH2:8][C:9]1[CH:14]=[CH:13][C:12]([NH:15][C:16](=[O:43])[C:17]2[CH:22]=[CH:21][C:20]([CH2:23][N:24]([CH2:37][C:38]3[NH:39][CH:40]=[CH:41][N:42]=3)[CH2:25][C:26]3[N:27]([CH2:31][CH2:32][O:33]COC)[CH:28]=[CH:29][N:30]=3)=[CH:19][CH:18]=2)=[CH:11][CH:10]=1)[CH2:5][CH2:6][CH3:7])[CH2:2][CH3:3].Cl>CO>[CH2:1]([N:4]([CH2:8][C:9]1[CH:10]=[CH:11][C:12]([NH:15][C:16](=[O:43])[C:17]2[CH:22]=[CH:21][C:20]([CH2:23][N:24]([CH2:25][C:26]3[N:27]([CH2:31][CH2:32][OH:33])[CH:28]=[CH:29][N:30]=3)[CH2:37][C:38]3[NH:39][CH:40]=[CH:41][N:42]=3)=[CH:19][CH:18]=2)=[CH:13][CH:14]=1)[CH2:5][CH2:6][CH3:7])[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 10438338HCID 10438338, compound

Product 1

HCID 49771574HCID 49771574, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The compound (60.0 mg) obtained in Example 92-3 was dissolved in methanol (5.0 ml) and then added with 1 mol/l hydrochloric acid (1.5 ml). The solution was concentrated and dried under reduced pressure, thereby obtaining hydrochloride (80.0 mg) of the subject compound as a white solid.

Workup

  1. concentrationThe solution was concentrated
  2. customdried under reduced pressure

Sources & evidence

ORD record
ord-c2f4b91ed7b6487981de8f450116298f
Source dataset
uspto-grants-2007_02
Patent number
US07176227B2

Reaction notes

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