Cinnamoylbenzene → HCID 11481281, compound

HRID 349154Notes

Reaction equation

HRID 349154 reaction equation
[C:1]1([CH:7]=[CH:8][C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:10])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>O>[C:11]1([C@@H:9]([OH:10])[CH2:8][CH2:7][C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 1

HCID 7189Cinnamoylbenzene

Product 1

HCID 11481281HCID 11481281, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Washed phaseolus aureus L (green grams) 50 g. were taken into a conical flask and allowed to soak in deionised water (400 ml) for a period of 24 hr. Chalcone (0.500 g; 0.0024 moles) (V) was added to the soaked phaseolus aureus L (green grams) in the above water, covered and allowed to shake for 24 hr at 15–20° C. Then the green grams were filtered off and washed with deionised water (3×100 ml). The combined filtrate was extracted with chloroform (3×500 ml). The chloroform layer was dried and the crude product obtained (240 mg). Pure 1,3-diphenyl-(1S)-propan-1-ol (VI) was obtained after column chromatography with silica gel using chloroform as eluent.

Workup

  1. washWashed phaseolus aureus L (green grams) 50 g
  2. customwere taken into a conical flask
  3. waitto shake for 24 hr at 15–20° C
  4. filtrationThen the green grams were filtered off
  5. washwashed with deionised water (3×100 ml)
  6. extractionThe combined filtrate was extracted with chloroform (3×500 ml)
  7. dry with materialThe chloroform layer was dried
  8. customthe crude product obtained (240 mg)

Sources & evidence

ORD record
ord-62899b36257a4a259e109184053f35e8
Source dataset
uspto-grants-2007_02
Patent number
US07179624B2

Reaction notes

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