Trifluoroacetic acid → HCID 13800254, compound

Participants

Reaction Steps

10.6 g of t-butyl [2-(4-chloropyridine-2-carboxamido)ethyl]carbamate were reacted with trifluoroacetic acid in an analogous manner to that described in Example 3, paragraph 2. The residue was converted into the hydrochloride which was recrystallized from methanol/ether, whereby there was obtained N-(2-aminoethyl)-4-chloropyridine-2-carboxamide hydrochloride as beige crystals, m.p. 228°-229°.

Provenance & Evidence