Ammonia → HCID 135732766, compound

Participants

Reaction Steps

A solution of ethyl 3-(1-formyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)propanoate (10 g) in a mixture of methanol (50 ml) and an aqueous solution of 28% ammonia (104 ml) was stirred at room temperature for 41 hours. After evaporation of the solvent in vacuo, the residue was triturated with diisopropyl alcohol, dried in vacuo to give 3-(2,3-dihydro-1H-imidazo[1,2-b]pyrazol-7-yl)propanamide (6.44 g).

Provenance & Evidence