反应详情

A mixture of ethyl(E)-3-[1-(4-benzyloxybenzyl)-3-phenyl-1H-pyrazol-4-yl]propenoate (12.13 g), 5% palladium-carbon (10.22 g) and tetrahydrofuran (100 ml) was stirred for 5 hours under a hydrogen atmosphere. After the palladium-carbon was removed by filtration, the filtrate was concentrated to obtain ethyl 3-[1-(4-hydroxybenzyl)-3-phenyl-1H-pyrazol-4-yl]propionate (9.52 g, yield 98%) as a colorless oily substance.

1. customAfter the palladium-carbon was removed by filtration
2. concentrationthe filtrate was concentrated