反应详情

A mixture of 2,2,3,3,4,4,4-heptafluoro-N-[4-(cyano)phenyl]butanamide (1.5 g,) sodium azide (1.55 g), ammonium chloride (1.28 g) and dimethylformamide (20 mL) was heated in a 130°-135° C. oil bath overnight. The reaction mixture was then poured onto 200 mL of water and the resulting solid was filtered off and recrystallized from ethanol. The product was dried at 100° C. overnight using an abderhalden (drying pistol) to give the title compound, m.p. 266°-268° C.

1. temperaturewas heated in a 130°-135° C. oil bath overnight
2. filtrationthe resulting solid was filtered off
3. customrecrystallized from ethanol
4. customThe product was dried at 100° C. overnight
5. customan abderhalden (drying pistol)