Hydrogen Bromide → HCID 18762647, compound

HRID 350606Notes

Reaction equation

HRID 350606 reaction equation
C(OC(=O)[N:10]([CH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[NH:26][CH:27]=[O:28])[CH:11]1[CH2:16][CH2:15][C:14](=[O:17])[NH:13][C:12]1=[O:18])C1C=CC=CC=1.Br>C(O)(=O)C>[O:18]=[C:12]1[CH:11]([NH:10][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=2[NH:26][CH:27]=[O:28])[CH2:16][CH2:15][C:14](=[O:17])[NH:13]1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 86760438HCID 86760438, compound

Product 1

HCID 18762647HCID 18762647, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

1.00 g of the product from stage 1 was reacted as described in Example 1, stage 5, with 3 ml of hydrobromic acid in acetic acid (33% HBr). After similar working-up, 0.79 g (91% of theory) of the title compound was obtained in the form of a yellowish solid, which was reacted further without purification.

Sources & evidence

ORD record
ord-380469d9b45547f9a8d91bccc637f23b
Source dataset
uspto-grants-2007_02
Patent number
US07183274B2

Reaction notes

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