反应详情

3-Benzyloxy-4-methoxypicolinic acid (8.3 g) was dissolved in 100 ml of methanol. Concentrated hydrochloric acid (2 ml) was added to the solution. The mixture was heated under reflux for 30 min. The reaction solution was concentrated under the reduced pressure. The residue was recrystallized from water-ethanol to give 3.6 g (yield 54.8%) of title compound as colorless powder.

1. temperatureThe mixture was heated
2. temperatureunder reflux for 30 min
3. concentrationThe reaction solution was concentrated under the reduced pressure
4. customThe residue was recrystallized from water-ethanol