Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,5-Di-(4-nitrophenyl)-3-n-propyl-3-azabicyclo[3.1.1]heptane-2,4-dione → 1,5-Di-(4-aminophenyl)-3-n-propyl-3-azabicyclo[3.1.1]heptane-2,4-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,5-Di-(4-nitrophenyl)-3-n-propyl-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 14872621 | — |
| 반응물 | Ethyl ether methylene chloride | HCID 21881112 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 1,5-Di-(4-aminophenyl)-3-n-propyl-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 20027820 | — |
반응 단계
In a manner analogous to that described in Example 12a, 0.4 g of 1,5-di-(4-nitrophenyl)-3-n-propyl-3-azabicyclo[3.1.1]heptane-2,4-dione are dissolved in 15 ml of ethyl acetate, hydrogenated in the presence of 80 mg of 5% palladium-on-carbon and worked up. Melting point 149°-150° (from ether/methylene chloride).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04764640 |
| 출처 데이터셋 | uspto-grants-1988_08 |
| ORD ID | ord-8912190ed3464e4091fb6280002f0b9a |
| 출처 메모 | uspto-grants-1988_08 |