HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-((Allyl(methyl)amino)methyl)thiazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | N-Methylallylamine | HCID 69391 | — |
| Reactant | 2-Thiazolamine, 4-(chloromethyl)-, hydrochloride (1:1) | HCID 73228 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-((Allyl(methyl)amino)methyl)thiazol-2-amine | HCID 21090603 | — |
Reaction Steps
N-allyl-N-methylamine (7.0 mg, 0.1 mmol), 2-amino-4-chloromethylthiazole hydrochloride (18.5 mg, 0.1 mmol), and potassium carbonate (30 mg, 0.21 mmol) are shaken in ethanol (1 mL) at room temperature for 18 hours. The mixture is filtered and the filtrate was condensed under vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07183300B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-6de76e9d87074e8c81db3041feaa73dd |
| Source note | uspto-grants-2007_02 |