HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Cyano-3-fluoro-phenoxy)-propionic acid tert-butyl ester → (R)-2-(4-Aminomethyl-3-fluoro-phenoxy)-propionic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Cyano-3-fluoro-phenoxy)-propionic acid tert-butyl ester | HCID 23529365 | — |
| Reactant | (R)-2-(4-Cyano-3-fluoro-phenoxy)-propionic acid tert-butyl ester | HCID 60128047 | — |
| Product | (R)-2-(4-Aminomethyl-3-fluoro-phenoxy)-propionic acid tert-butyl ester | HCID 60128053 | — |
Reaction Steps
The compound of Formula (5.0.20) was prepared in a manner analogous to that described in Preparation 10, substituting (R)-2-(4-Cyano-3-fluoro-phenoxy)-propionic acid tert-butyl ester for the corresponding (+)-2-(4-cyano-3-fluoro-phenoxy)-propionic acid tert-butyl ester material.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07183293B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-d113e33e2d214176811e9cc8856f3bc8 |
| Source note | uspto-grants-2007_02 |