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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 351198Generated: October 30, 2026

HCID 21090991, compound → 5-[4-(Benzyloxy)phenyl]-1-(4-methoxyphenyl)-1H-pyrazol-3-amine

https://huagongshe.com/reaction/351198

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 21090991HCID 21090991—
CatalystManganese dioxideHCID 14801—
SolventDimethylformamideHCID 6228—
Product5-[4-(Benzyloxy)phenyl]-1-(4-methoxyphenyl)-1H-pyrazol-3-amineHCID 21090988—

Reaction Conditions

Temperature60 °C

Reaction Steps

MnO2 (3.5 g) was added to a solution of 5-[4-(benzyloxy)phenyl]-1-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-3-amine obtained by Example 14-1 (12.54 g). in N,N-dimethylformamide (65 ml) and the mixture was stirred at 60° C. for 2 hrs. MnO2 (5.3 g) was added and the mixture was stirred at 60° C. for 1 hr.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07183306B2
Source datasetuspto-grants-2007_02
ORD IDord-4d591be82b604a20b0783b741d4aedc1
Source noteuspto-grants-2007_02