HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-[4-(Benzyloxy)phenyl]-1-(4-methoxyphenyl)-N,N-dimethyl-1H-pyrazol-3-amine → 4-[3-(Dimethylamino)-1-(4-methoxyphenyl)-1H-pyrazol-5-yl]phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-[4-(Benzyloxy)phenyl]-1-(4-methoxyphenyl)-N,N-dimethyl-1H-pyrazol-3-amine | HCID 21090994 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-[3-(Dimethylamino)-1-(4-methoxyphenyl)-1H-pyrazol-5-yl]phenol | HCID 135737379 | — |
Reaction Steps
A mixture of 5-[4-(benzyloxy)phenyl]-1-(4-methoxyphenyl) -N,N-dimethyl-1H-pyrazol-3-amine obtained by Example 15 (0.83 g) and 10% Pd-C 50% wet (160 mg) in acetic acid (8 ml) was hydrogenated under H2 1 atm at room temperature for 10 hrs.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07183306B2 |
| Source dataset | uspto-grants-2007_02 |
| ORD ID | ord-10601d6cee5e4244ac12166b6906661c |
| Source note | uspto-grants-2007_02 |