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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 351205Generated: October 31, 2026

Ethanol → HCID 135737383, compound

https://huagongshe.com/reaction/351205

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
ReactantAmmonium formateHCID 2723923—
ReactantHCID 21091002HCID 21091002—
CatalystPalladiumHCID 23938—
SolventWaterHCID 962—
SolventTetrahydrofuranHCID 8028—
ProductHCID 135737383HCID 135737383—

Reaction Steps

To a solution of ammonium formate (954 mg) in water (2 ml) were added ethanol (10 ml), a solution of 5-[4-(benzyl-oxy)phenyl]-3-isopropoxy-1-(4-methoxyphenyl)-1H-pyrazole obtained by Example 36 (2.09 g) in tetrahydrofuran (10 ml), and 10% palladium on carbon 50% wet (200 mg) successively. The mixture was refluxed for 1 hr.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07183306B2
Source datasetuspto-grants-2007_02
ORD IDord-425d52ecb9e94ebe93305b53be008499
Source noteuspto-grants-2007_02