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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 351223Generated: October 30, 2026

Pyridine → HCID 21090955, compound

https://huagongshe.com/reaction/351223

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantAcetic AnhydrideHCID 7918—
ReactantHCID 21091035HCID 21091035—
SolventDichloromethaneHCID 6344—
ProductHCID 21090955HCID 21090955—

Reaction Steps

To a mixture of N-(2-{4-[1-(4-hydroxyphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl]phenoxy}ethyl)urea obtained by Example 81 (148.5 mg) in dichloromethane (1.5 ml) was added pyridine (163 μL) and acetic anhydride (45 μL), and the mixture was stirred at room temperature for 1 hr and stirred under reflux for 3 hrs.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07183306B2
Source datasetuspto-grants-2007_02
ORD IDord-28a30d553df3442ca1cf777b3eee4b1c
Source noteuspto-grants-2007_02