Hydrochloric Acid → HCID 21090819, compound

Participants

Reaction Steps

A 4M solution of HCl in dioxane (2 ml) was added to a solution of ter-butyl (2-{4-[3-isopropenyl-1-(6-methoxy-3-pyridinyl)-1H-pyrazol-5-yl]phenoxy}ethyl)carbamate (269.7 mg) in CH2Cl2 (2 ml) . The reaction mixture was stirred at ambient temperature for 2 hours, then, was concentrated in vacuo to give (2-{4-[3-isopropenyl-1-(6-methoxy-3-pyridinyl)-1H-pyrazol-5-yl]phenoxy}ethyl)amine dihydrochloride (259 mg) as an amorphous powder.

Provenance & Evidence