Acetic Anhydride → HCID 14300140, compound

Participants

Reaction Steps

To a solution (233 mL) of 2-fluoro-3-nitroaniline (18.2 g, 116 mol) in pyridine was added acetic anhydride (27.4 mL, 291 mmol) and the mixture was stirrred at room temperature for 16 hrs. The reaction solution was concentrated under reduced pressure and the obtained residue was treated with isopropyl ether to give the title compound (19.2 g) as a powder.

Provenance & Evidence