Acrylonitrile → 1-Pyrrolidinepropionitrile

HRID 351489Notes

Reaction equation

[C:1](#[N:4])[CH:2]=[CH2:3].[NH:5]1[CH2:9][CH2:8][CH2:7][CH2:6]1>>[N:5]1([CH2:3][CH2:2][C:1]#[N:4])[CH2:9][CH2:8][CH2:7][CH2:6]1

Participants

Reactant 2

HCID 7855Acrylonitrile

HCID 31268Pyrrolidine

Product 1

HCID 1177431-Pyrrolidinepropionitrile

Procedure

At 20 to 30° C., 5.31 g of acrylonitrile was added to 7.11 g of pyrrolidine, which was stirred for 2 hours. Purification by vacuum distillation yielded 1-pyrrolidine-propiononitrile.

Workup

customPurification
distillationby vacuum distillation

Sources & evidence

ORD record: ord-8eb4190cc02c421da9ccea55598b59b1
Source dataset: uspto-grants-2004_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06743564B2

Reaction notes

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