Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tetrahydrofuran → 4-Morpholinebutanenitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | Morpholine | HCID 8083 | — |
| 반응물 | 4-Bromobutyronitrile | HCID 21412 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 4-Morpholinebutanenitrile | HCID 294574 | 91% |
반응 단계
A mixture of 10.0 g of 4-bromobutyronitrile, 14.7 g of morpholine and 40 g of tetrahydrofuran was heated under reflux for 10 hours. The reaction solution was cooled, diluted with diethyl ether, filtered, and concentrated in vacuum. Purification by vacuum distillation yielded 9.4 g of 4-morpholinobutyronitrile (boiling point: 85° C./50 Pa, yield: 91%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06743564B2 |
| 출처 데이터셋 | uspto-grants-2004_06 |
| ORD ID | ord-b658d2c40e2545b09adf29762d0185ae |
| 출처 메모 | uspto-grants-2004_06 |