1-Decanol → HCID 86587064, compound

HRID 351506Notes

Reaction equation

HRID 351506 reaction equation
[CH2:1]([O:3][CH:4]([CH2:10][C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1)[C:5]([O:7][CH2:8][CH3:9])=[O:6])[CH3:2].[CH2:18](O)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]CC>CCCCCCC>[CH2:1]([O:3][C@@H:4]([CH2:10][C:11]1[CH:12]=[CH:13][C:14]([OH:17])=[CH:15][CH:16]=1)[C:5]([O:7][CH2:8][CH2:9][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[O:6])[CH3:2].[CH2:1]([O:3][C@H:4]([CH2:10][C:11]1[CH:12]=[CH:13][C:14]([OH:17])=[CH:15][CH:16]=1)[C:5]([O:7][CH2:8][CH3:9])=[O:6])[CH3:2]

Participants

4

Reactant 2

HCID 81741-DecanolHCID 11791243Ethyl 2-ethoxy-3-(4-hydroxyphenyl)propanoate

Product 1

HCID 86587064HCID 86587064, compound

Reagents, catalysts & solvents 1

HCID 8900HeptaneSolvent

Procedure

Ethyl (2RS) (+/−) 2-ethoxy-3-(4-hydroxyphenyl)propanoate (9 mg) was added to a solution containing: Immobilised Mucor miehei lipase immobilised on accurel EP 100 load :187 klu/g (18 mg), n-decanol 14 μl, heptane 0.9 ml and 4 Å molecular sieves. The reaction mixture was shaken at room temperature and analysed at different times (maximum 7 h). The reaction mixtures were analysed by the gradient HPLC method 2 and by the chiral HPLC method 4.

Workup

  1. additioncontaining
  2. customanalysed at different times (maximum 7 h)
  3. customThe reaction mixtures

Sources & evidence

ORD record
ord-386b9455291f4dd8b64cc7f04698ad6f
Source dataset
uspto-grants-2004_06
Patent number
US06743608B2

Reaction notes

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