1-Benzyloxycarbonyl-4-(4-hexyloxyphenyl)-4-hydroxypiperidine → 4-[4-(Hexyloxy)phenyl]piperidin-4-OL

Participants

Reaction Steps

To a solution of 1-benzyloxycarbonyl-4-(4-hexyloxyphenyl)-4-hydroxypiperidine (1.4 g) in methanol (28 ml) was added dry 10% palladium on carbon (0.7 g) and stirred for 6 hours under hydrogen atmosphere. The palladium on carbon was filtered off, and the filtrate was evaporated under reduced pressure to give 4-(4-hexyloxyphenyl)-4-hydroxypiperidine (0.74 g).

Provenance & Evidence