HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 2-[3-(4-Carbamimidoylphenyl)ureido]acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 15521690 | HCID 15521690 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-[3-(4-Carbamimidoylphenyl)ureido]acetic acid | HCID 22713560 | 113.3% |
Reaction Steps
A solution of 2-[3-(4-carbamimidoylphenyl)ureido]acetic acid ethyl ester (24.48 g, 0.0926 mol, compound of example 3c) in ethanol (100 ml) and NaOH (3.705 g, 0.0926 mol, in 5 ml water) was stirred for 22 h at room temperature. The precipitate was filtered off and washed with ethanol to give 24.78 g of the title compound. MS 258.2 (M)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06743790B2 |
| Source dataset | uspto-grants-2004_06 |
| ORD ID | ord-e723ce618a7b47ea87d22b3b969162fa |
| Source note | uspto-grants-2004_06 |