Isobutanol → isobutyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

HRID 35166Notes

Reaction equation

HRID 35166 reaction equation
[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16]#[N:17])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH2:18]([OH:22])[CH:19]([CH3:21])[CH3:20]>>[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16](=[NH:17])[O:22][CH2:18][CH:19]([CH3:21])[CH3:20])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 6560IsobutanolHCID 198338865,7-dihydro-6H-dibenz[c,e]azepine-6carbonitrile

Product 1

HCID 20041728isobutyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

Procedure

starting from 5,7-dihydro-6H-dibenz[c,e]azepine-6-carbonitrile and isobutanol there is obtained isobutyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate as a resinous product, 1H-NMR(CDCl3): 1.07 [d, CH(CH3)2 ], 2.1 (m, 1H), 3.95 (d, CH2), 4.25 (s, 4H), 4.55 (broad s, NH), 7.3-7.7 (8H);

Sources & evidence

ORD record
ord-7eda7b44d9cb422dba2777eaa53bed5a
Source dataset
uspto-grants-1988_08
Patent number
US04766115

Reaction notes

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