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HRID351745

反应详情

EQUATION

反应方程式

HRID 351745 的结构方程式

REACTANTS

反应物

4
结构：C#C[Si](C)(C)C
HCID66111

Trimethylsilylacetylene

C5H10Si

结构：C#CC(C)(O)c1ccccc1
HCID92098

2-Phenylbut-3-yn-2-ol

C10H10O

结构：CC(C)NC(=O)c1cn(-c2cccc(Br)c2)c2ncccc2c1=O
HCID12991318

未命名化合物

结构：CC(C)(O)c1ccc(Br)nc1
HCID22391973

6-Bromo-α,α-dimethyl-3-pyridinemethanol

C8H10BrNO

PRODUCTS

生成物

1
结构：CC(C)(O)c1ccc(C#C[Si](C)(C)C)nc1
HCID22714299

α,α-Dimethyl-6-[2-(trimethylsilyl)ethynyl]-3-pyridinemethanol

C13H19NOSi

PROCEDURE

实验过程

Following the procedure of EXAMPLE 15, but substituting the product 2-bromo-5-(1-hydroxy-1-methylethyl)pyridine from present Step 1 for N-isopropyl-1-(3-bromophenyl)-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide and trimethylsilylacetylene for 2-phenyl-3-butyn-2-ol, the 5-(1-hydroxy-1-methylethyl)-2-[(trimethylsilyl)ethynyl]pyridine compound was obtained.