HCID 22714705, compound → HCID 22714704, compound

HRID 351918Notes

Reaction equation

HRID 351918 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[CH2:10][CH:9]([C:11]([O:13][CH3:14])=[O:12])[C:8]=2[CH:15]=1)([O-])=O>[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]2[CH2:10][CH:9]([C:11]([O:13][CH3:14])=[O:12])[C:8]=2[CH:15]=1

Participants

3

Reactant 1

HCID 22714705HCID 22714705, compound

Product 1

HCID 22714704HCID 22714704, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

9.74 g of methyl 5-nitro-1-benzocyclobutanecarboxylate are hydrogenated for 6 hours 30 minutes, at ambient temperature and atmospheric pressure, in the presence of 10% Pd/C. After filtration and concentration under reduced pressure, the expected product is isolated.

Workup

  1. filtrationAfter filtration and concentration under reduced pressure

Sources & evidence

ORD record
ord-356fc177bc7846cdac2ccd035550752c
Source dataset
uspto-grants-2004_06
Patent number
US06743818B2

Reaction notes

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