Sodium Hydroxide → HCID 15612245, compound

HRID 35196Notes

Reaction equation

HRID 35196 reaction equation
Cl.[N:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH2:8][C:9]2[CH:18]=[CH:17][C:16]3[C:11](=[CH:12][CH:13]=[C:14]([C:19]([OH:21])=[O:20])[CH:15]=3)[CH:10]=2)[CH:3]=1.[OH-].[Na+]>C(Cl)Cl>[N:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH2:8][C:9]2[CH:18]=[CH:17][C:16]3[C:11](=[CH:12][CH:13]=[C:14]([C:19]([OH:21])=[O:20])[CH:15]=3)[CH:10]=2)[CH:3]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 704078322-(3-Pyridylmethyl)naphthalene-6-carboxylic acid hydrochloride

Product 1

HCID 15612245HCID 15612245, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A suspension of 2-(3-pyridylmethyl)naphthalene-6-carboxylic acid hydrochloride in 100 ml of methylene chloride is stirred with a stoichiometric amount of dilute aqueous sodium hydroxide solution until the salt is completely dissolved. The organic layer is separated, washed with water, dried over magnesium sulfate and evaporated to yield 2-(3-pyridylmethyl)naphthalene-6-carboxylic acid.

Workup

  1. dissolutionis completely dissolved
  2. customThe organic layer is separated
  3. washwashed with water
  4. dry with materialdried over magnesium sulfate
  5. customevaporated

Sources & evidence

ORD record
ord-3af67bb12ea247339371119e2a5e933d
Source dataset
uspto-grants-1988_08
Patent number
US04766127

Reaction notes

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