2-Chloro-N-(2-methylpropyl)-6-methyl-3-nitropyridin-4-amine → 2-Chloro-N4-(2-methylpropyl)-6-methylpyridin-3,4-diamine

Participants

Reaction Steps

2-Chloro-N-(2-methylpropyl)-6-methyl-3-nitropyridin-4-amine (5.00 g) from Part A, toluene (100 ml), and 5% platinum on carbon (3.5 g) were added to a Parr shaker and placed on a hydrogenator at a hydrogen pressure of 345 kPa for 4 hours. The reaction, monitored by HPLC, was complete, and the resulting reaction mixture was filtered through a fluted filter paper and then through a folded No.2 Whatman filter. The solvent was removed from the filtrate under reduced pressure, and the resulting oil (4.14 g) was carried on to the next step.

Provenance & Evidence