Potassium Hydroxide → HCID 178506416, compound

HRID 352043Notes

Reaction equation

HRID 352043 reaction equation
[C:1]1([CH2:7][C:8]([NH:10][C-:11]2[CH:15]=[CH:14][CH:13]=[CH:12]2)=O)[CH:6]=[CH:5][CH:4]=CC=1.[C-:16]1([NH:21][C:22](=O)[CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=CC=2)[CH:20]=[CH:19][CH:18]=[CH:17]1.[Fe+2:31].[OH-].[K+]>>[C:8]1([NH:10][C-:11]2[CH:12]=[CH:13][CH:14]=[CH:15]2)[CH:4]=[CH:5][CH:6]=[CH:1][CH:7]=1.[C-:16]1([NH:21][C:22]2[CH:23]=[CH:24][CH:29]=[CH:28][CH:27]=2)[CH:17]=[CH:18][CH:19]=[CH:20]1.[Fe+2:31]

Participants

3

Reactant 2

HCID 14797Potassium HydroxideHCID 178520221HCID 178520221, compound

Product 1

HCID 178506416HCID 178506416, compound

Procedure

(0.55 mmol) of 1,1′-bis(phenylacetamido)ferrocene in 30 ml of argon-saturated ethanol (96%) were heated under argon with 2 g (35.6 mmol) of potassium hydroxide for 16 hours under reflux. After cooling, the reaction mixture was (without inert gas) diluted with 30 ml of argon-saturated water, transferred to a separating funnel and extracted a number of times with ether. The combined ether phases were dried over sodium sulfate, filtered and evaporated under argon in a high vacuum.

Workup

  1. temperatureunder reflux
  2. temperatureAfter cooling
  3. additiondiluted with 30 ml of argon-saturated water
  4. customtransferred to a separating funnel
  5. extractionextracted a number of times with ether
  6. dry with materialThe combined ether phases were dried over sodium sulfate
  7. filtrationfiltered
  8. customevaporated under argon in a high vacuum

Sources & evidence

ORD record
ord-d6f7b3952a544ad6a6a0f618850e24f9
Source dataset
uspto-grants-2004_06
Patent number
US06743932B2

Reaction notes

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