反应详情

A solution of the product from step (b) (2.80 g) and sodium iodide (20 g) in acetone (100 ml) was heated under reflux for 20 h. The mixture was filtered, evaporated, dissolved in water (50 ml) and extracted with ethyl acetate (three times). The organic extracts were washed with water, dried (magnesium sulphate) and evaporated to give the title compound (3.22 g).

1. temperatureunder reflux for 20 h
2. filtrationThe mixture was filtered
3. customevaporated
4. dissolutiondissolved in water (50 ml)
5. extractionextracted with ethyl acetate (three times)
6. washThe organic extracts were washed with water
7. dry with materialdried (magnesium sulphate)
8. customevaporated