HCID 86742343, compound → 3-(13-Nitro-6-methyl-8alpha-ergolinyl)-1,1-diethylurea

Participants

Reaction Steps

One millimole of 3-(2,3-dihydro-6-methyl-13-nitro-8α-ergolinyl)-1,1-diethylurea is dissolved in 10 ml of methylene chloride, and 2 g of pyrolusite in solid form is added thereto. The mixture is then stirred for 2 hours at room temperature. After removing excess pyrolusite by filtration, the filtrate is evaporated. The residue is chromatographed on silica gel with methylene chloride/methanol (5%), thus obtaining 210 mg of 3-(6-methyl-13-nitro-8α-ergolinyl)-1,1-diethylurea.

Provenance & Evidence