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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 352207Generated: October 30, 2026

Hydrochloric Acid → HCID 22713722, compound

https://huagongshe.com/reaction/352207

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantLithium HydroxideHCID 3939—
ReactantHCID 28564689HCID 28564689—
SolventWaterHCID 962—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 22713722HCID 22713722—

Reaction Steps

To a solution of (6-methoxy-pyridin-3-ylamino)-acetic acid methyl ester, 113 mg (0.58 mmol) in 10 mL of dioxane was added a solution of 70 mg (2.9 mmol) of lithium hydroxide in 10 mL of water. The reaction mixture was stirred for three hours, acidified to pH=1 with 5 N HCl and concentrated to dryness to yield the crude desired product which was carried on without further purification. MS (IS) 183.1 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06743794B2
Source datasetuspto-grants-2004_06
ORD IDord-30e30f6194a844a1b0b8689fbf4c2a31
Source noteuspto-grants-2004_06