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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 352363Generated: October 25, 2026

cis-1-Benzyl-2,6-dimethylpiperazine → cis-7-(4-Benzyl-3,5-dimethylpiperazin-1-yl)-6-methoxyquinoline

https://huagongshe.com/reaction/352363

Reaction equation

Participants

RoleNameHCIDCharge
Reactantcis-1-Benzyl-2,6-dimethylpiperazineHCID 12284911—
Reactant7-Bromo-6-methoxyquinolineHCID 14566897—
Productcis-7-(4-Benzyl-3,5-dimethylpiperazin-1-yl)-6-methoxyquinolineHCID 69837656—

Reaction Steps

The title compound was prepared from cis-1-benzyl-2,6-dimethylpiperazine (Org. Prep. Proc. 1976, 8, 19) and 7-bromo-6-methoxyquinoline (J. Org. Chem. 1990, 55, 2019) using a similar procedure to Description 2 (75%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06747030B1
Source datasetuspto-grants-2004_06
ORD IDord-366abd74ab324242870f5e3b0ea0df0c
Source noteuspto-grants-2004_06