Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 352369Generated: October 30, 2026

2-Fluoro-3-(trifluoromethyl)phenylacetic acid → HCID 44402887, compound

https://huagongshe.com/reaction/352369

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-3-(trifluoromethyl)phenylacetic acidHCID 2737588—
Reactantcis-5-Methoxy-6-(3,4,5-trimethylpiperazin-1-yl)indolineHCID 69836129—
ProductHCID 44402887HCID 44402887—

Reaction Steps

The title compound was prepared from 2-fluoro-3-trifluoromethylphenylacetic acid (155 mg, 0.70 mmole) and D3 (150 mg, 0.54 mmole) using a similar procedure to Example 8. The product was obtained as a pale yellow oil (210 mg, 81%), which was converted to its hydrochloride salt as a beige solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06747030B1
Source datasetuspto-grants-2004_06
ORD IDord-c5d20f0c98624bae96a6bcc57e721702
Source noteuspto-grants-2004_06