HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 35245Generated: October 29, 2026
Water → 3-(2-Chloro-6-fluorophenyl)-5-acetylisoxazole
https://huagongshe.com/reaction/35245
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 1-[3-(2-Chloro-6-fluorophenyl)-5-isoxazolyl]-ethanol | HCID 14814685 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-(2-Chloro-6-fluorophenyl)-5-acetylisoxazole | HCID 14814686 | — |
Reaction Steps
To a solution of 30 g (124 mmol) of 1-[3-(2-chloro-6-fluorophenyl)-5-isoxazolyl]-ethanol in 187 ml of acetic acid maintained under stirring at 5° C. were added dropwise 9.07 (90.7 mmol) of CrO3 in 9.34 of water and 132 ml of acetic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04766137 |
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| Source dataset | uspto-grants-1988_08 |
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| ORD ID | ord-46bd94bcb7bf45a7a2e065bbd4e8d3ea |
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| Source note | uspto-grants-1988_08 |
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