HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiourea → 2-Amino-4-(3-bromo-5-isoxazolyl)-thiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 3-Bromo-5-(bromoacetyl)isoxazole | HCID 13626973 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-4-(3-bromo-5-isoxazolyl)-thiazole | HCID 14814698 | — |
Reaction Steps
A mixture of 32.4 g (120.4 mol) of 5-bromoacetyl-3-bromoisoxazole and 18.4 g (240 mmol) of thiourea in 400 ml of anhydrous ethanol was refluxed for 90 minutes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04766137 |
| Source dataset | uspto-grants-1988_08 |
| ORD ID | ord-9644ee042c6549bb8ea8936e03738844 |
| Source note | uspto-grants-1988_08 |