反应详情

A mixture of 1 mmol of 4,5-dihydro-5-(4-nitrobenzoyl)pyrrolo[1,2-a]quinoxaline in 10 ml of ethyl alcohol and 10 ml of ethyl acetate containing 0.2 g of 10% Pd/C is hydrogenated for 5 hours. The reaction mixture is filtered through a pad of diatomaceous earth. The filtrate is concentrated in vacuo to a solid which is purified by flash chromatography to give the desired product, m.p. 225°-228° C.

1. filtrationThe reaction mixture is filtered through a pad of diatomaceous earth
2. concentrationThe filtrate is concentrated in vacuo to a solid which
3. customis purified by flash chromatography