Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 352879Generated: October 30, 2026

Water → HCID 23694151, compound

https://huagongshe.com/reaction/352879

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantLithium HydroxideHCID 3939—
ReactantHCID 22709528HCID 22709528—
SolventTetrahydrofuranHCID 8028—
ProductHCID 23694151HCID 23694151—

Reaction Steps

To a solution of 6-(tert-butoxycarbonyl)-2-methoxycarbonyl-4,5,6,7-tetrahydrooxazolo[5,4-c]pyridine (311 mg) in tetrahydrofuran (8.0 ml) were added water (2.0 ml) and lithium hydroxide (25.0 mg) at room temperature. After stirring for 10 minutes, the reaction mixture was distilled under reduced pressure to remove the solvent, whereby the title compound (280 mg) was obtained as a colorless solid. The residue was provided for the subsequent reaction without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06747023B1
Source datasetuspto-grants-2004_06
ORD IDord-6d442c26d3cc4987a786a57e33665155
Source noteuspto-grants-2004_06