Trifluoroacetic acid → HCID 22708225, compound

Participants

Reaction Steps

Similarly to the procedure of Example 1-9, 170 mg (0.318 mmol) of tert-butyl 3-(4-{[(2-(4-methoxy-2,5-dimethylphenyl)amino-2-oxoethyl)(2-furylmethyl)amino]methyl}phenyl)-2,2-dimethylpropionate (Example 1-2) are reacted with 1 ml of trifluoroacetic acid in 1 ml of dichloromethane to give 133 mg (87%) of 3-(4-{[(2-(4-methoxy-2,5-dimethylphenyl)amino-2-oxoethyl)(2-furylmethyl)amino]methyl}phenyl)-2,2-dimethylpropionic acid.

Provenance & Evidence