Trifluoroacetic acid → HCID 22708164, compound

Participants

Reaction Steps

Similarly to the procedure of Example 1-9, 115 mg (0.237 mmol) of tert-butyl 2-(4-{[(1-{[(4-methoxy-2,5-dimethylphenyl)amino]carbonyl}propyl)amino]methyl}phenoxy)-2-methylpropionate (Example 1-8) are reacted with 0.46 ml (5.93 mmol) of trifluoroacetic acid in 3 ml of dichloromethane to give 100 mg (93%) of 2-(4-{[(1-{[(4-methoxy-2,5-dimethylphenyl)amino]carbonyl}propyl)amino]methyl}phenoxy)-2-methylpropionic acid.

Provenance & Evidence