Benzyl Bromide → [5-(Benzyloxy)-1H-indol-3-yl]acetonitrile

HRID 353233Notes

Reaction equation

HRID 353233 reaction equation
[CH2:1](Br)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH:9][C:10]1[CH:11]=[C:12]2[C:16](=[CH:17][CH:18]=1)[NH:15][CH:14]=[C:13]2[CH2:19][C:20]#[N:21]>>[CH2:1]([O:9][C:10]1[CH:11]=[C:12]2[C:16](=[CH:17][CH:18]=1)[NH:15][CH:14]=[C:13]2[CH2:19][C:20]#[N:21])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 51506175-HYDROXYINDOLE-3-ACETONITRILE

Product 1

HCID 252139[5-(Benzyloxy)-1H-indol-3-yl]acetonitrile

Procedure

The title compound was prepared by a method analogous to that described in Example 1 from benzyl bromide and 5-hydroxyindole-3-acetonitrile. MS ES (MH−)=263.

Sources & evidence

ORD record
ord-acd14fc4bf9342dbac2db814d0f11732
Source dataset
uspto-grants-2004_06
Patent number
US06750242B1

Reaction notes

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