Hydrochloric Acid → HCID 22708904, compound

HRID 353403Notes

Reaction equation

HRID 353403 reaction equation
[I:1][C:2]1[C:7]([N+:8]([O-])=O)=[C:6]([I:11])[C:5]([N+:12]([O-])=O)=[C:4]([I:15])[C:3]=1[C:16]1[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=1.[Sn].Cl>>[I:1][C:2]1[C:7]([NH2:8])=[C:6]([I:11])[C:5]([NH2:12])=[C:4]([I:15])[C:3]=1[C:16]1[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 5352426Tin atomHCID 22708902HCID 22708902, compound

Product 1

HCID 22708904HCID 22708904, compound

Procedure

The nitro groups of 2′,4′,6′-triiodo-3′,5′-bis(nitro)-4-methylbiphenyl (7) are reduced to amines by reaction with tin and hydrochloric acid to yield 2′,4′,6′-triiodo-3′,5′-bis(amino)-4-methylbiphenyl (8). The product is used in the preparation of Examples 1, 2, and 3 of the present invention.

Sources & evidence

ORD record
ord-350a9ee034ff4c58859c583ddb0ab527
Source dataset
uspto-grants-2004_06
Patent number
US06751290B2

Reaction notes

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