Guanidine → HCID 178513081, compound

HRID 353440Notes

Reaction equation

HRID 353440 reaction equation
C[O:2][C:3]([C:5]1[CH:6]=[N:7][N:8]([C:13]2[CH:22]=[CH:21][CH:20]=[C:19]3[C:14]=2[CH:15]=[CH:16][CH:17]=[N:18]3)[C:9]=1[CH:10]1[CH2:12][CH2:11]1)=O.[NH2:23][C:24]([NH2:26])=[NH:25]>>[CH:10]1([C:9]2[N:8]([C:13]3[CH:22]=[CH:21][CH:20]=[C:19]4[C:14]=3[CH:15]=[CH:16][CH:17]=[N:18]4)[N:7]=[CH:6][C:5]=2[C:3]([NH:25][C:24]([NH2:26])=[NH:23])=[O:2])[CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 3520GuanidineHCID 11449248Methyl 5-cyclopropyl-1-(5-quinolyl)pyrazole-4-carboxylate

Product 1

HCID 178513081HCID 178513081, compound

Procedure

coupling said 5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carboxylic acid methyl ester with guanidine to form N-(5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carbonyl)-guanidine.

Sources & evidence

ORD record
ord-c7bc8408b8d046ec85190ab2462d849c
Source dataset
uspto-grants-2004_06
Patent number
US06753334B2

Reaction notes

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