Guanidine → HCID 178513081, compound

HRID 353443Notes

Reaction equation

HRID 353443 reaction equation
[CH:1]1([C:4]2[N:8]([C:9]3[CH:18]=[CH:17][CH:16]=[C:15]4[C:10]=3[CH:11]=[CH:12][CH:13]=[N:14]4)[N:7]=[CH:6][C:5]=2[C:19]([OH:21])=O)[CH2:3][CH2:2]1.[NH2:22][C:23]([NH2:25])=[NH:24]>>[CH:1]1([C:4]2[N:8]([C:9]3[CH:18]=[CH:17][CH:16]=[C:15]4[C:10]=3[CH:11]=[CH:12][CH:13]=[N:14]4)[N:7]=[CH:6][C:5]=2[C:19]([NH:24][C:23]([NH2:25])=[NH:22])=[O:21])[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 3520GuanidineHCID 113004451H-Pyrazole-4-carboxylic acid, 5-cyclopropyl-1-(5-quinolinyl)-

Product 1

HCID 178513081HCID 178513081, compound

Procedure

coupling said 5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carboxylic acid with guanidine to form N-(5-cyclopropyl-1-quinolin-5-yl-1H-pyrazole-4-carbonyl)-guanidine.

Sources & evidence

ORD record
ord-e7ee2121013a4c2db27171eb486c1c48
Source dataset
uspto-grants-2004_06
Patent number
US06753334B2

Reaction notes

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