Guanidine → HCID 178504788, compound

HRID 353444Notes

Reaction equation

HRID 353444 reaction equation
C[O:2][C:3]([C:5]1[CH:6]=[N:7][N:8]([C:13]2[CH:18]=[CH:17][C:16]([S:19]([CH3:22])(=[O:21])=[O:20])=[CH:15][C:14]=2[Cl:23])[C:9]=1[CH:10]1[CH2:12][CH2:11]1)=O.[NH2:24][C:25]([NH2:27])=[NH:26]>>[CH:10]1([C:9]2[N:8]([C:13]3[CH:18]=[CH:17][C:16]([S:19]([CH3:22])(=[O:20])=[O:21])=[CH:15][C:14]=3[Cl:23])[N:7]=[CH:6][C:5]=2[C:3]([NH:26][C:25]([NH2:27])=[NH:24])=[O:2])[CH2:11][CH2:12]1

Participants

3

Reactant 2

HCID 3520GuanidineHCID 698588105-cyclopropyl-1-(2-chloro-4-methanesulfonylphenyl)-1H-pyrazole-4-carboxylic acid methyl ester

Product 1

HCID 178504788HCID 178504788, compound

Procedure

coupling said 5-cyclopropyl-1-(2-chloro-4-methanesulfonylphenyl)-1H-pyrazole-4-carboxylic acid methyl ester with guanidine to form N-{5-cyclopropyl-1-(2-chloro-4-methanesulfonylphenyl)-1H-pyrazole-4-carbonyl}-guanidine.

Sources & evidence

ORD record
ord-bcf25d7a40294a44a029a042fffb7e3f
Source dataset
uspto-grants-2004_06
Patent number
US06753334B2

Reaction notes

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