3,4-Dichlorobenzyl chloride → HCID 783950, compound

HRID 353527Notes

Reaction equation

[NH:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4].[Cl:8][C:9]1[CH:10]=[C:11]([CH:14]=[CH:15][C:16]=1[Cl:17])[CH2:12]Cl>>[OH:4][CH2:3][CH2:2][N:1]([CH2:12][C:11]1[CH:14]=[CH:15][C:16]([Cl:17])=[C:9]([Cl:8])[CH:10]=1)[CH2:5][CH2:6][OH:7]

Participants

Reactant 2

HCID 76093,4-Dichlorobenzyl chloride

HCID 8113Diethanolamine

Product 1

HCID 783950HCID 783950, compound

Procedure

2-[(2-Hydroxy-ethyl)-(3,4-dichlor-benzyl)-amino]-ethanol was prepared according to the general method as outlined in Example 1 (Step 4). Starting from diethanolamine (4.84 g, 46 mmol) and 3,4-dichlorobenzyl chloride (8.97 g, 46 mmol), 9.4 g of the product was isolated. Yield, (78%); white solid; MS: 264.3 (M+H)+.

Sources & evidence

ORD record: ord-0b86f497574b47f38766e7fb8f893cd7
Source dataset: uspto-grants-2004_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06753337B2

Reaction notes

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