反应详情

To a solution of carnitine chloride (2.0 g; 10 m moles) in TFA (5 cc), 4-carbomethoxy butyryl chloride (1.65 cc; 12 m moles) was added and the resulting reaction mixture was kept at room temperature under stirring for 24 hours. To this mixture anhydrous ethyl ether was then added. A solid formed which was filtered off and crystallized from hot isopropanol. M.P. 130°-132° C.

1. customthe resulting reaction mixture
2. customwas kept at room temperature
3. customA solid formed which
4. filtrationwas filtered off
5. customcrystallized from hot isopropanol