反应详情

温度

65 °C

In a four necked 100 ml flask equipped with a condenser, a dropping funnel and a thermometer, tributylamine (20.0 g, 108 mmoles) was charged and warmed to 65° C. Monochloromethyl 2-trifluoromethyl-3,3,3-trifluoropropanoate (4.88 g, 20 mmol) was dropwise added thereto while stirring. The reaction was continued at the same temperature as above for 3 hours while stirring. The gas evolved from a top of the condenser was washed with an alkaline solution, dried with alumina and cooled. The resultant liquid was distilled to give 2-trifluoromethyl-3,3,3-trifluoropropene (2.49 g). Yield, 76 %.

1. customIn a four necked 100 ml flask equipped with a condenser, a dropping funnel
2. customwas continued at the same temperature as above for 3 hours
3. stirringwhile stirring
4. washwas washed with an alkaline solution
5. customdried with alumina
6. temperaturecooled
7. distillationThe resultant liquid was distilled